Kangen Glucuro‑lactone Capsules

Brand Name: 康尔®(Kangen®)
Generic Name: Glucuro‑lactone
Strength: 0.1 g per capsule
Manufacturer: SUZHOU NO.3 PHARMACEUTICAL FACTORY CO.,LTD.
Marketing Authorization Holder: SUZHOU NO.3 PHARMACEUTICAL FACTORY CO.,LTD.
Approval Date in China: 2002‑06‑14
Registration Number: National Drug Approval No. H32025525
Storage: Store in sealed, dry place and protected from light

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1. Indications and Usage
Liver Disorders: Adjunctive treatment for acute and chronic hepatitis, fatty liver, and cirrhosis.
Toxicity and Poisoning: Used to alleviate liver and kidney damage caused by drug toxicity, heavy metal poisoning, or alcohol abuse.
2. Dosage and Administration
Adults: The usual dosage is 1 to 2 capsules (200–400 mg) per dose, taken 3 times daily.
Severe Cases: In severe conditions, the dosage may be increased to 3 capsules per dose, 3 times daily.
Administration: Capsules should be swallowed with water.
3. Mechanism of Action
Detoxification: Glucurono-lactone participates in the body’s metabolic processes and combines with toxic substances to form stable, non-toxic conjugates, which are then excreted in the urine.
Hepatoprotection: It improves liver cell function, reduces liver inflammation, and promotes the regeneration of liver cells.
4. Safety and Warnings
Contraindications: Contraindicated in patients with known hypersensitivity to the drug or its components.
Special Populations: Use with caution in pregnant women, breastfeeding women, and children. Safety and efficacy in these populations have not been fully established.
Precautions: Patients should be monitored for signs of liver function improvement or worsening during treatment.
5. Adverse Reactions and Clinical Research
Common Adverse Reactions: Rarely, gastrointestinal discomfort, nausea, or vomiting may occur.
Hypersensitivity: Allergic reactions, including skin rash and pruritus, may occur in rare cases.
6. Drug Interactions
Interaction Profile: No significant drug interactions have been reported. It is generally compatible with other hepatoprotective agents.
Precautions: Concomitant use with other medications may cause interactions; consultation with a physician or pharmacist is advised.
7. Pharmaceutical Information
Active Ingredient: Glucurono-lactone.
Strength: Typically 200 mg per capsule.
Appearance: Hard gelatin capsules, usually containing white or off-white powder or granules.
Storage: Keep in a light-resistant, tightly closed container in a dry place, protected from moisture.

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