Combizym Mutiase and Pancreatin Coated Tablets

1. Indications and Usage
Digestive Disorders: Primarily indicated for the treatment of indigestion and lack of appetite.
2. Dosage and Administration
Adults: The usual dosage is 2 to 3 tablets per dose, 3 times daily.
Administration: The tablets should be swallowed orally with water.
Special Populations: For children, pregnant women, breastfeeding women, and the elderly, use should be under the guidance of a physician or pharmacist.
3. Mechanism of Action
Enzymatic Hydrolysis: The drug contains pancreatic enzymes (lipase, amylase, protease) and pepsin.
Digestive Promotion: Pancreatic lipase decomposes fats into glycerin and fatty acids, amylase converts starch to sugar, and protease decomposes proteins to peptones. Pepsin also converts proteins to peptones.
Synergistic Effect: The combined use of these enzymes promotes digestion and stimulates appetite.
4. Safety and Warnings
Acid Instability: The drug is easily destroyed in an acidic environment; tablets must not be chewed or crushed.
Hypersensitivity: Contraindicated in patients with known hypersensitivity to the drug or its components.
Storage: Keep the drug protected from light, tightly sealed, and stored in a dry place.
5. Adverse Reactions and Clinical Research
Common Adverse Reactions: Adverse reactions are currently unclear.
Management: No specific management is typically required for mild, transient discomfort.
6. Drug Interactions
Aluminum Preparations: The use of aluminum preparations may affect the efficacy of this drug and should not be used concurrently.
Other Medications: If used concurrently with other medications, consultation with a physician or pharmacist is required.
7. Pharmaceutical Information
Active Ingredients: Pancreatin (300 mg) and Pepsin (13 mg) per tablet.
Appearance: Double-layer coated tablets, with pancreatin as the inner layer and pepsin as the outer layer.
Storage: Protect from light, keep tightly sealed, store in a dry place.
Shelf Life: 24 months.