{"id":3772,"date":"2026-06-05T09:36:14","date_gmt":"2026-06-05T16:36:14","guid":{"rendered":"https:\/\/xpharma.com.cn\/?p=3772"},"modified":"2026-06-05T09:36:16","modified_gmt":"2026-06-05T16:36:16","slug":"qihan-biotech%ef%bc%9ain-vivo-car-t-clinical-data-were-disclosed-by-qihan-biotech","status":"publish","type":"post","link":"https:\/\/xpharma.com.cn\/index.php\/drug-development\/qihan-biotech%ef%bc%9ain-vivo-car-t-clinical-data-were-disclosed-by-qihan-biotech\/","title":{"rendered":"Qihan Biotech\uff1aIn vivo CAR-T clinical data were disclosed by Qihan Biotech."},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"700\" height=\"350\" src=\"http:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/w700h350z1l10t104c5.jpg\" alt=\"Qihan Biotech\" class=\"wp-image-3773\" style=\"object-fit:cover;width:420px;height:310px\" srcset=\"https:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/w700h350z1l10t104c5.jpg 700w, https:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/w700h350z1l10t104c5-300x150.jpg 300w, https:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/w700h350z1l10t104c5-500x250.jpg 500w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><figcaption class=\"wp-element-caption\">Qihan Biotech<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">This morning, Qihan Biotech reported preliminary positive clinical data for its in vivo CAR-T therapy. Qihan Biotech did not disclose specific information about its in vivo CAR-T pipeline. It is only known that the company&#8217;s first in vivo CAR-T program is a dual-targeting in vivo CAR-T developed for the treatment of multiple myeloma. It was developed based on Qihan Biotech&#8217;s proprietary precision-targeting in vivo CAR-T platform technology, which can avoid non-specific effects on tumor cells and phagocytic cells, precisely target T cells, address the issue of antigen masking, and ensure the safety and long-term efficacy of in vivo CAR-T therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">According to a report released by Qihan Biotech at the 2025 ASH Annual Meeting, the company has developed a lentivirus-based in vivo CAR-T platform. Through the engineering of binder-fusogen proteins, this platform reduces cytokine release, precisely controls early T cell stimulation, and exhibits rapid receptor internalization without sustained formation of TCR signaling complexes. This preserves the resting T cell metabolic profile and prevents upregulation of exhaustion markers. Consequently, the platform achieves highly specific, built-in safety features for &#8220;silent&#8221; CAR delivery while maintaining a functionally quiescent state of T cells.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Currently, Qihan Biotech&#8217;s in vivo CAR-T program has advanced to the clinical stage, with an ongoing investigator-initiated trial (IIT). Dosing has been completed in four patients with refractory multiple myeloma.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Buy In Vivo CAR-T&nbsp;online from China and save up to 80% on costs . no insurance needed . compare prices from a certified HongKong pharmacy .with fast shipping. Contact us now on WhatsApp to get the latest prices.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This morning, Qihan Biotech reported preliminary positive clinical data for its in vivo CAR-T therapy. Qihan Biotech did not disclose specific information about its in vivo CAR-T pipeline. It is only known that the company&#8217;s first in vivo CAR-T program is a dual-targeting in vivo CAR-T developed for the treatment of multiple myeloma. It was [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3773,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-3772","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-development"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Qihan Biotech\uff1aIn vivo CAR-T clinical data were disclosed by Qihan Biotech. - Xpharma China<\/title>\n<meta name=\"description\" content=\"Qihan Biotech\uff1aIn vivo CAR-T clinical data were disclosed by Qihan Biotech. - Xpharma China\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/xpharma.com.cn\/index.php\/drug-development\/qihan-biotech\uff1ain-vivo-car-t-clinical-data-were-disclosed-by-qihan-biotech\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Qihan Biotech\uff1aIn vivo CAR-T clinical data were disclosed by Qihan Biotech. - 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