{"id":3775,"date":"2026-06-05T09:40:59","date_gmt":"2026-06-05T16:40:59","guid":{"rendered":"https:\/\/xpharma.com.cn\/?p=3775"},"modified":"2026-06-05T09:41:00","modified_gmt":"2026-06-05T16:41:00","slug":"sichuan-biokin%ef%bc%9abl-m14d1-initiates-its-first-global-phase-iii-trial","status":"publish","type":"post","link":"https:\/\/xpharma.com.cn\/index.php\/drug-development\/sichuan-biokin%ef%bc%9abl-m14d1-initiates-its-first-global-phase-iii-trial\/","title":{"rendered":"Sichuan Biokin\uff1aBL-M14D1\u00a0initiates its first global Phase III trial."},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"474\" height=\"306\" src=\"http:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/OIP-C-2.webp\" alt=\"Sichuan Biokin\" class=\"wp-image-3776\" style=\"object-fit:cover;width:420px;height:310px\" srcset=\"https:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/OIP-C-2.webp 474w, https:\/\/xpharma.com.cn\/wp-content\/uploads\/2026\/06\/OIP-C-2-300x194.webp 300w\" sizes=\"(max-width: 474px) 100vw, 474px\" \/><figcaption class=\"wp-element-caption\">Sichuan Biokin<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">On June 4 local time, the ClinicalTrials website showed that SystImmune, a wholly-owned subsidiary of Baili Tianheng, registered a Phase III clinical trial of BL-M14D1 in combination with Tecentriq&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&nbsp;for the first-line treatment of extensive-stage small cell lung cancer. According to public information, this is the first Phase III trial initiated for this drug.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This is a global, open-label, multicenter Phase III clinical trial designed to evaluate the efficacy and safety of BL-M14D1 in combination with atezolizumab compared with standard treatment regimens in adult patients with previously untreated extensive-stage small cell lung cancer (ES-SCLC). The study plans to enroll approximately 550 patients, with the primary endpoint being progression-free survival (PFS).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BL-M14D1 is a novel DLL3-targeting ADC developed by Baili Tianheng. It precisely recognizes and binds to tumor cells, and upon internalization, releases a highly potent topoisomerase I inhibitor Ed-04 to achieve targeted killing. Baili Tianheng is also exploring the therapeutic potential of BL-M07D1 in small cell lung cancer (SCLC), neuroendocrine carcinoma (NEC), and other solid tumors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Buy In BL-M14D1&nbsp;online from China and save up to 80% on costs . no insurance needed . compare prices from a certified HongKong pharmacy .with fast shipping. Contact us now on WhatsApp to get the latest prices.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On June 4 local time, the ClinicalTrials website showed that SystImmune, a wholly-owned subsidiary of Baili Tianheng, registered a Phase III clinical trial of BL-M14D1 in combination with Tecentriq&nbsp; &nbsp;for the first-line treatment of extensive-stage small cell lung cancer. According to public information, this is the first Phase III trial initiated for this drug. This [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3776,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-3775","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-development"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sichuan Biokin\uff1aBL-M14D1\u00a0initiates its first global Phase III trial. - Xpharma China<\/title>\n<meta name=\"description\" content=\"Sichuan Biokin\uff1aBL-M14D1\u00a0initiates its first global Phase III trial. - Xpharma China\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/xpharma.com.cn\/index.php\/drug-development\/sichuan-biokin\uff1abl-m14d1-initiates-its-first-global-phase-iii-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sichuan Biokin\uff1aBL-M14D1\u00a0initiates its first global Phase III trial. - 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