{"id":3800,"date":"2026-06-06T08:32:56","date_gmt":"2026-06-06T15:32:56","guid":{"rendered":"https:\/\/xpharma.com.cn\/?p=3800"},"modified":"2026-06-06T08:32:57","modified_gmt":"2026-06-06T15:32:57","slug":"northland%ef%bc%9anl003-received-marketing-approval","status":"publish","type":"post","link":"https:\/\/xpharma.com.cn\/index.php\/news\/northland%ef%bc%9anl003-received-marketing-approval\/","title":{"rendered":"Northland\uff1aNL003 received marketing approval"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Saiduomingji Injection, a Category 1 new drug independently developed by Northland Biotech, is the world&#8217;s first approved plasmid-based gene therapy drug. It is indicated for the treatment of ulcers caused by severe limb ischemia (CLI) in patients who are not suitable for revascularization or have poor surgical outcomes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CLI is an end-stage manifestation of peripheral arterial disease. Patients often suffer from refractory ulcers, rest pain, and a high risk of amputation. Conventional surgical options are applicable to a limited population, and there has long been a lack of effective pharmacological treatments in clinical practice.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Saiduomingji is administered via intramuscular injection of plasmid DNA. Upon transfection of striated muscle cells, it continuously secretes bioactive HGF isoforms, activating the HGF\/C-MET pathway. This promotes the establishment of microcirculation and collateral circulation, restores blood flow to the ischemic region, and reduces the immunogenicity risks associated with gene therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Buy NL003\u00a0online from China and save up to 80% on costs . no insurance needed . compare prices from a certified HongKong pharmacy .with fast shipping. Contact us now on WhatsApp to get the latest prices.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Saiduomingji Injection, a Category 1 new drug independently developed by Northland Biotech, is the world&#8217;s first approved plasmid-based gene therapy drug. It is indicated for the treatment of ulcers caused by severe limb ischemia (CLI) in patients who are not suitable for revascularization or have poor surgical outcomes. CLI is an end-stage manifestation of peripheral [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3108,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-3800","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Northland\uff1aNL003 received marketing approval - Xpharma China<\/title>\n<meta name=\"description\" content=\"Northland\uff1aNL003 received marketing approval - Xpharma China\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/xpharma.com.cn\/index.php\/news\/northland\uff1anl003-received-marketing-approval\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Northland\uff1aNL003 received marketing approval - 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