{"id":4211,"date":"2026-06-11T09:20:08","date_gmt":"2026-06-11T16:20:08","guid":{"rendered":"https:\/\/xpharma.com.cn\/?p=4211"},"modified":"2026-06-11T09:20:10","modified_gmt":"2026-06-11T16:20:10","slug":"henlius-%ef%bc%9ahetroniflyserplulimabreceived-marketing-approval","status":"publish","type":"post","link":"https:\/\/xpharma.com.cn\/index.php\/news\/henlius-%ef%bc%9ahetroniflyserplulimabreceived-marketing-approval\/","title":{"rendered":"Henlius\u00a0\uff1aHetronifly\u00aeSerplulimabreceived marketing approval"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">On June 9, the NMPA official website showed that a new indication for Henlius&#8217; PD-1 monoclonal antibody Serplulimab has been approved for marketing \u2014 in combination with oxaliplatin and tegafur\/gimeracil\/oteracil for neoadjuvant treatment of resectable gastric cancer with tumor PD-L1 expression CPS \u22655, followed by single-agent adjuvant therapy after surgery. This application had previously received dual designations from the CDE for Breakthrough Therapy and Priority Review. With this approval, Serplulimab becomes the first PD-(L)1 monoclonal antibody in China approved for perioperative treatment of gastric cancer, offering a new treatment option beyond chemotherapy for this patient population.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Serplulimab (H drug) is a PD-1 monoclonal antibody with a differentiated mechanism independently developed by Henlius. It not only exhibits stronger PD-1 internalization, reducing PD-1 receptors on the T cell surface to achieve rapid and potent immune activation, but also reduces PD-1 recruitment of the co-stimulatory molecule CD28, thereby preserving CD28 signaling to a greater extent, enhancing downstream AKT protein activity, and promoting sustained T cell activation.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Buy <strong>Hetronifly\u00aeSerplulimab<\/strong>&nbsp;from China and save up to 80% on costs . no insurance needed . compare prices from a certified HongKong pharmacy .with fast shipping. Contact us now on WhatsApp to get the latest prices.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>On June 9, the NMPA official website showed that a new indication for Henlius&#8217; PD-1 monoclonal antibody Serplulimab has been approved for marketing \u2014 in combination with oxaliplatin and tegafur\/gimeracil\/oteracil for neoadjuvant treatment of resectable gastric cancer with tumor PD-L1 expression CPS \u22655, followed by single-agent adjuvant therapy after surgery. This application had previously received [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":3376,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-4211","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"blocksy_meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Henlius\u00a0\uff1aHetronifly\u00aeSerplulimabreceived marketing approval - Xpharma China<\/title>\n<meta name=\"description\" content=\"Henlius\u00a0\uff1aHetronifly\u00aeSerplulimabreceived marketing approval - Xpharma China\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/xpharma.com.cn\/index.php\/news\/henlius-\uff1ahetroniflyserplulimabreceived-marketing-approval\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Henlius\u00a0\uff1aHetronifly\u00aeSerplulimabreceived marketing approval - 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