1. Indications and Usage
\nRespiratory Diseases:
\nTreatment of acute and chronic respiratory diseases associated with abnormal mucus secretion and impaired mucus transport.
\nExamples: Acute and chronic bronchitis, pneumonia, bronchiectasis, and COPD.
\nTarget Symptom: Mucus accumulation, thick sputum, and difficulty in expectoration (coughing up phlegm).
\n2. Dosage and Administration
\nRoute of Administration:
\nFor Inhalation ONLY using a nebulizer. Do not use orally or by injection.
\nRecommended Dosage (Typical):
\nAdults and Children >12 Years: 2\u20133 mL per dose, 1\u20132 times daily.
\nChildren (2\u201312 Years): 2 mL per dose, 1\u20132 times daily.
\nInfants (<2 Years): 1 mL per dose, 1\u20132 times daily.
\nCritical Administration Instructions:
\nDilution: It is recommended to dilute the solution with 0.9% Sodium Chloride Injection (Normal Saline) at a 1:1 ratio to ensure optimal humidification and prevent airway irritation.
\nHygiene: The inhaler\/nebulizer must be cleaned after each use. Discard any remaining solution in the cup after the session.
\n3. Mechanism of Action
\nMucolysis:
\nAmbroxol breaks down the acidic mucopolysaccharide fibers in the sputum, thereby reducing the viscosity of the mucus and making it easier to cough up.
\nSurfactant Stimulation:
\nIt stimulates the production and secretion of pulmonary surfactant in type II alveolar cells, which helps stabilize the airways and improves mucociliary clearance.
\nCiliary Activity:
\nIt enhances the movement of cilia on the respiratory epithelium, accelerating the transport of mucus out of the lungs.
\n4. Safety and Warnings
\nBronchospasm Risk:
\nDeep inhalation may cause bronchospasm. Patients with asthma or hyper-reactive airways should use bronchodilators prior to inhalation.
\nSputum Clearance:
\nIf a large amount of mucus is liquefied but not expelled (especially in patients with impaired ciliary function), it may cause airway obstruction. Frequent suctioning or chest physiotherapy may be required.
\nSkin Reactions:
\nSerious skin reactions (e.g., Stevens-Johnson Syndrome, TEN) have been rarely reported. Discontinue immediately if rash or mucosal lesions occur.
\n5.Adverse Reactions
\nMost Common:
\nMild irritation of the throat or airways, coughing, nausea, dysgeusia (bad taste), and rarely, allergic reactions.
\n6.Drug Interactions
\nAntibiotics:
\nConcurrent use with antibiotics (e.g., Amoxicillin, Cephalexin, Erythromycin, Doxycycline) may increase antibiotic concentration in lung tissue\/sputum, potentially enhancing efficacy.
\nCough Suppressants:
\nAvoid concomitant use with strong antitussives (cough suppressants). Reducing the cough reflex while increasing sputum volume can lead to dangerous mucus accumulation (“plugging”).
\nAlkaline Solutions:
\nDo not mix with alkaline injectable solutions (pH > 6.3), as this causes precipitation and drug inactivation.
\n7.Pharmaceutical Information
\nChemical Composition:
\nActive Ingredient: Ambroxol Hydrochloride.
\nAppearance: Clear, colorless to slightly yellow solution.
\nPackaging: Typically available in single-dose plastic vials (e.g., 2 mL\/ampoule).
\nStorage: Store below 30\u00b0C. Keep in the original package to protect from light.<\/p>\n","protected":false},"excerpt":{"rendered":"
Brand Name: \u6613\u5b89\u5e73 \u00ae(Yi An Ping\u00ae)
\nGeneric Name: Ambroxol Hydrochloride
\nStrength: 15 mg per 2 mL single-dose unit, 24 units per box
\nManufacturer: Hanmi Pharm. Co., Ltd. (Republic of Korea)
\nMarketing Authorization Holder: Hanmi Pharm. Co., Ltd.
\nDomestic Sub-packager & Agent: Beijing Hanmi Pharmaceutical Co., Ltd.
\nApproval Date in China: September 16, 2019
\nRegistration Number: H20190041
\nStorage: Store at room temperature below 25\u00b0C, protect from light. After opening the single-dose vial, use immediately. Refer to the package insert for detailed storage rules.<\/p>\n
Price&Cost:Contact Us now for the best price of Ambroxol Hydrochloride\uff08Yi An Ping\uff09<\/p>\n","protected":false},"featured_media":4173,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[66],"product_tag":[],"class_list":["post-4172","product","type-product","status-publish","has-post-thumbnail","product_cat-inhalation-preparation","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\n