1. Indications and Usage
\nSevere Bacterial Infections:
\nTreatment of serious infections caused by susceptible microorganisms, including sepsis, bacteremia, and severe infections in immunocompromised patients (e.g., ICU, burn units).
\nSpecific Site Infections:
\nLower respiratory tract infections (including pneumonia), intra-abdominal and biliary tract infections, complicated urinary tract infections, and severe skin and soft tissue infections.
\nCNS Infections:
\nMeningitis (particularly caused by Haemophilus influenzae, Neisseria meningitidis, Pseudomonas aeruginosa, and Streptococcus pneumoniae).
\n2. Dosage and Administration
\nRoute of Administration:
\nFor Intravenous (IV) Infusion ONLY.
\nRecommended Dosage:
\nAdults: Typically 1 g to 2 g every 8 to 12 hours.
\nSevere Infections: Up to 3 g to 6 g per day divided into multiple doses.
\nRenal Impairment: Dosage must be adjusted based on creatinine clearance.
\nCritical Administration Instructions:
\nMixing: Activate the double-chamber bag to mix the powder and the 5% Glucose Injection.
\nCompatibility: This formulation is specifically designed for 5% Glucose Injection and should not be mixed with other drugs.
\n3. Mechanism of Action
\nCell Wall Inhibition:
\nCeftazidime is a third-generation cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs).
\nBactericidal Effect:
\nIt inhibits bacterial cell wall synthesis, exhibiting high activity against Gram-negative bacteria, including Pseudomonas aeruginosa, while being stable against many \u03b2-lactamases.
\n4. Safety and Warnings
\nHypersensitivity:
\nSerious and occasionally fatal hypersensitivity (anaphylactic) reactions. Contraindicated in patients with severe penicillin allergy.
\nClostridioides difficile-Associated Diarrhea:
\nBroad-spectrum antibiotics may alter normal gut flora, leading to pseudomembranous colitis.
\nRenal and Hepatic Function:
\nMonitor renal and hepatic parameters, especially during prolonged therapy.
\nNeurotoxicity:
\nHigh doses in patients with renal impairment may cause seizures or encephalopathy.
\n5.Adverse Reactions and Clinical Research
\nMost Common Adverse Reactions:
\nNausea, vomiting, diarrhea, injection site reactions (phlebitis), and skin rash.
\nLaboratory Abnormalities:
\nTransient elevation of liver enzymes, serum creatinine, and eosinophilia.
\n6.Drug Interactions
\nAminoglycosides:
\nPotentially increased risk of nephrotoxicity if used concomitantly (must be administered separately).
\nProbenecid:
\nMay increase and prolong ceftazidime serum concentrations.
\nAnticoagulants:
\nMay enhance the anticoagulant effect of warfarin.
\n7.Pharmaceutical Information
\nChemical Composition:
\nPowder Chamber: Contains Ceftazidime (as monohydrate) and Sodium Carbonate.
\nLiquid Chamber: Contains 5% Glucose Injection.
\nAppearance: White to off-white powder; colorless to slightly yellow liquid.
\nPackaging: Double-chamber bag (e.g., 1.0 g powder + 50 mL liquid).
\nStorage: Store at controlled room temperature.<\/p>\n","protected":false},"excerpt":{"rendered":"
Brand Name:\u5408\u76ca\u5b9a \u00ae\uff08Heyiding\u00ae\uff09
\nGeneric Name: Ceftazidime for Injection and 5% Glucose Injection
\nStrength: Powder compartment: 1.0 g ceftazidime; Liquid compartment: 50 mL 2.5 g glucose, dual-chamber bag
\nManufacturer: Hunan Kelun Pharmaceutical Co., Ltd.
\nMarketing Authorization Holder: Sichuan Kelun Pharmaceutical Co., Ltd.
\nApproval Date in China: September 24, 2021
\nRegistration Number: \u56fd\u836f\u51c6\u5b57H20213747
\nStorage: Store below 25\u00b0C, protected from light and moisture; do not freeze. Refer to the full package insert for detailed storage specifications.<\/p>\n
Price&Cost:Contact Us now for the best price of Ceftazidime for Injection and 5% Glucose Injection\uff08Heyiding\uff09<\/p>\n","protected":false},"featured_media":4388,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[25,73],"product_tag":[],"class_list":["post-4387","product","type-product","status-publish","has-post-thumbnail","product_cat-injection","product_cat-chinese-innovative-drug","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\n