Luoye Carbazochrome Sodium Sulfonate Tablets

1. Indications and Usage
Capillary Bleeding: Indicated for the treatment of various types of capillary bleeding, such as gastrointestinal bleeding, pulmonary hemorrhage, and epistaxis.
Surgical Support: Used to prevent or treat excessive bleeding during and after surgical procedures.
2. Dosage and Administration
Standard Dose: The usual dosage for adults is 10–20 mg (1–2 tablets) per dose, taken orally three times daily.
Administration: Can be taken with or without food.
Duration: Treatment duration should be determined by the severity of the bleeding and the patient’s response.
3. Mechanism of Action
Vascular Stabilization: Carbazochrome sodium sulfonate promotes the regeneration of damaged capillary endothelium and increases the density and toughness of capillary walls.
Hemostatic Effect: It shortens the bleeding time and helps stabilize the capillary barrier, thereby reducing hemorrhage.
4. Safety and Warnings
Renal and Hepatic Impairment: Use with caution in patients with renal or hepatic dysfunction, as the drug may accumulate.
Pregnancy and Lactation: Safety has not been fully established in pregnant or breastfeeding women. Use only if the potential benefit justifies the risk.
Precautions: Patients should be monitored for signs of hypersensitivity or adverse reactions during treatment.
5. Adverse Reactions and Clinical Research
Gastrointestinal: Occasional epigastric discomfort, nausea, vomiting, and abdominal pain.
Dermatologic: Occasional skin rashes or pruritus.
Other: Rare cases of hypersensitivity reactions have been reported.
6. Drug Interactions
Interaction Profile: Drug interactions are currently not well-documented. Caution is advised when combining with other agents affecting hemostasis or coagulation.
7. Pharmaceutical Information
Active Ingredient: Carbazochrome Sodium Sulfonate.
Strengths: Typically available as 10 mg tablets.
Appearance: White or slightly yellowish tablets, often film-coated.
Storage: Store in a tight, light-resistant container, protected from moisture.