How much does CRESEMBA (Isavuconazonium Sulfate Capsules) Cost& price without insurance in China?
CRESEMBA® is the commercial brand name of Isavuconazonium Sulfate Capsules, a novel triazole antifungal agent developed by Basilea Pharmaceutica Deutschland GmbH. As a prodrug, it is rapidly converted in vivo to isavuconazole, which exerts its antifungal activity by inhibiting the enzyme cytochrome P450 14α-demethylase (CYP51), thereby blocking ergosterol synthesis in fungal cell membranes.
Main Indications
Treatment of adult patients with invasive aspergillosis and invasive mucormycosis.
Common Side Effects
Common adverse reactions: Elevated liver enzyme levels, nausea, vomiting, diarrhea, abdominal pain, headache, dyspnea, hypokalemia, rash, and fatigue.
Severe but rare adverse events: Severe hepatotoxicity, hypersensitivity reactions, arrhythmia, and Stevens-Johnson syndrome.
Approval Status in China
CRESEMBA® (Isavuconazonium Sulfate Capsules, 100mg) was officially approved for marketing in China in December 2021. It is currently a prescription drug and included in China’s Category B medical insurance.
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