How much does Retsevmo (Selpercatinib Capsules) Cost& price without insurance in China?
Retsevmo® is the commercial brand name of Selpercatinib Capsules, an orally active, highly selective rearranged during transfection (RET) inhibitor developed by Eli Lilly and Innovent Biologics. It exerts anti-tumor activity by specifically inhibiting the kinase activity of RET, thereby blocking downstream signaling pathways and suppressing the proliferation and survival of tumor cells harboring RET gene fusions or activating mutations.
Main Indications
Treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring RET gene fusions;
Treatment of adult and pediatric patients aged 12 years and older with advanced or metastatic thyroid cancer harboring RET mutations, including medullary thyroid carcinoma (MTC) and differentiated thyroid carcinoma (DTC).
Common Side Effects
Common adverse reactions: Dry mouth, diarrhea, hypertension, fatigue, edema, rash, constipation, nausea, abdominal pain, and cough.
Laboratory abnormalities: Decreased neutrophil count, decreased platelet count, decreased hemoglobin, increased transaminases, and increased creatinine.
Severe but manageable risks: Interstitial lung disease/pneumonitis, severe hypertension, hepatotoxicity, hemorrhage, and QT interval prolongation.
Approval Status in China
Retsevmo® (Selpercatinib Capsules, 80mg) was officially approved for marketing in China in October 2023. It is currently a prescription drug and pending inclusion in China’s national medical insurance.
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