How much does Tracleer (Bosentan Tablets) Cost& price without insurance in China?
Tracleer® is the commercial brand name of Bosentan Tablets, an orally active dual endothelin receptor antagonist developed by Actelion. It blocks endothelin ETₐ and ETᵦ receptors on pulmonary vascular smooth muscle to relax pulmonary arteries, reduce pulmonary vascular resistance and slow vascular remodeling.
Main Indications
Treatment of pulmonary arterial hypertension (WHO functional class II–III) in adults to improve exercise tolerance and delay disease progression.
Common Side Effects
Common mild adverse reactions: Headache, flushing, peripheral edema, nasal congestion and dyspepsia.
Laboratory abnormalities: Dose-related liver enzyme elevation and anemia.
Severe but manageable risks: Severe hepatic injury, fetal toxicity and severe hypersensitivity.
Approval Status in China
Tracleer® (Bosentan Tablets,125mg, domestic Chinese brand name: Quankeli) was officially approved for marketing in China in 2006. It is currently a prescription drug included in China’s Category B medical insurance.
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