How much does Zavesca (Miglustat Capsules) Cost& price without insurance in China?

Zavesca® is the commercial brand name of Miglustat Capsules, an orally active glucosylceramide synthase inhibitor developed by Janssen. It reduces the synthesis of glycosphingolipids, thereby decreasing the accumulation of toxic substrates in lysosomes.

Main Indications
Treatment of mild to moderate type 1 Gaucher disease in adult patients who are not eligible for enzyme replacement therapy.
Long-term treatment of progressive neurological manifestations in adult and pediatric patients with Niemann-Pick type C disease.

Common Side Effects
Common mild adverse reactions: Diarrhea, flatulence, abdominal pain, weight loss, and tremor.
Laboratory abnormalities: Decreased platelet count, decreased hemoglobin, and elevated liver enzymes.
Severe but uncommon risks: Peripheral neuropathy, severe gastrointestinal disturbances, and thrombocytopenia.

Approval Status in China
Zavesca® (Miglustat Capsules, 0.1g) was officially approved for marketing in China in 2017. It is currently a prescription drug included in China’s Category B medical insurance.

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