How much does ZEPZELCA (Lurbinectedin for Injection) Cost& price without insurance in China?
ZEPZELCA® is the commercial brand name of Lurbinectedin for Injection, a synthetic marine-derived alkylating antitumor agent. It binds to the minor groove of tumor cell DNA, inhibits gene transcription and induces apoptosis of malignant cells, while also regulating the tumor microenvironment to exert anti-tumor activity.
Main Indications
Monotherapy for adult patients with metastatic small cell lung cancer (SCLC) who have progressed after platinum-containing first-line chemotherapy.
Common Side Effects
Common mild adverse reactions: Fatigue, neutropenia, thrombocytopenia, anemia, nausea, vomiting, elevated liver transaminases and constipation.
Laboratory abnormalities: Decreased neutrophil count, reduced platelet count, decreased hemoglobin, elevated ALT/AST.
Severe but uncommon risks: Severe myelosuppression complicated by infection, grade 3–4 liver injury, infusion-related reactions and interstitial lung disease.
Approval Status in China
ZEPZELCA® (Lurbinectedin for Injection, 4 mg per vial) obtained official marketing approval in China in May 2024. It is a prescription cytotoxic anti-tumor injectable drug.
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