How much does STEGLATRO (Ertugliflozin Tablets) Cost& price without insurance in China?
STEGLATRO® is the commercial brand name of Ertugliflozin Tablets, developed by MSD. It is an oral sodium-glucose cotransporter 2 inhibitor. It blocks glucose reabsorption in renal tubules to promote urinary glucose excretion, lowering blood sugar independent of pancreatic beta cell function, and delivers additional benefits on weight management and cardiovascular protection.
Main Indications
Improvement of glycemic control in adult patients with type 2 diabetes mellitus, available as monotherapy or combined with other hypoglycemic agents;
Cardiovascular risk reduction for type 2 diabetic patients with confirmed atherosclerotic cardiovascular disease.
Clinical Research
Global multicenter clinical trials fully validated its clinical value. Glycemic control trials demonstrated sustained reduction of blood glucose and glycated hemoglobin through urinary glucose excretion mechanism. Cardiovascular outcome trials verified its cardiovascular protective effects for high-risk diabetic patients. Tolerability comparison studies reflected mild genitourinary adverse events as the main mild reactions with low hypoglycemia incidence under single-agent treatment. Long-term follow-up research confirmed stable sustained efficacy and controllable overall safety profile during long-term medication.
Common Side Effects
Common mild adverse reactions: Genital mycotic infection, urinary tract infection, polyuria, thirst and fatigue;
Laboratory abnormalities: Rare transient slight elevation of creatinine and ketone bodies;
Severe but uncommon risks: Severe hypoglycemia (mainly when combined with insulin or sulfonylureas), diabetic ketoacidosis, acute kidney injury and lower limb amputation risk.
Approval Status in China
STEGLATRO® (specification 5mg, 14 tablets per box) obtained marketing approval in China in 2020. It is an oral prescription anti-diabetic drug included in China’s Category B medical insurance catalogue.
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