Abilify Maintena® is the commercial brand name of Aripiprazole for Injection, a long-acting injectable atypical antipsychotic. It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, delivering sustained therapeutic concentrations after intramuscular injection to stabilize psychiatric symptoms.
Main Indications
Maintenance treatment of schizophrenia in adult patients who have achieved stable therapeutic effect with oral aripiprazole.
Clinical Research
Global pivotal clinical trials demonstrated that monthly injectable aripiprazole effectively maintains symptom control and reduces relapse risk for schizophrenia patients. Compared with oral formulations, it significantly improves medication adherence and brings long-term clinical benefits for patients with poor oral drug compliance.
Common Side Effects
The frequent adverse reactions include injection site discomfort, akathisia, insomnia, headache and anxiety. Other possible reactions comprise restlessness, gastrointestinal symptoms and mild weight fluctuation.
Approval Status in China
Original drug Abilify Maintena® (Aripiprazole for Injection) was officially approved for marketing in China in 2021. It is a prescription long-acting antipsychotic agent.
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