Kefenqi Troxipide Capsules

1. Indications and Usage
Peptic Ulcer Disease: Treatment of gastric ulcers.
Gastritis: Improvement of gastric mucosal lesions (such as erosion, bleeding, redness, and swelling) associated with acute gastritis and chronic gastritis during acute exacerbation.
2. Dosage and Administration
Adults: Oral administration after meals. The usual dosage is 0.1 g (1 capsule) three times daily.
Individualization: Dosage may be adjusted according to the patient’s age and symptoms.
Administration: The capsules should be taken orally after meals.
3. Mechanism of Action
Mucosal Protection: Troxipide is a novel gastroprotective agent that enhances gastric mucosal defense factors to promote the repair of ulcerated areas.
Specific Effects: It has no effect on gastric acid secretion but increases gastric mucosal blood flow and promotes tissue repair. Animal studies suggest it prevents and treats experimental gastritis and acute gastric mucosal lesions.
4. Safety and Warnings
Hypersensitivity: Contraindicated in patients with a known hypersensitivity to troxipide or any components of the formulation.
Special Populations: Use with caution in pregnant women, nursing mothers, the elderly, and children, as safety has not been fully established in these groups.
Monitoring: If significant adverse reactions occur, discontinue the medication immediately.
5. Adverse Reactions and Clinical Research
Gastrointestinal Effects: Occasionally, constipation, abdominal distension, burning sensation in the chest, or nausea may occur.
Hepatic Effects: Elevations in liver function markers (e.g., ALT, AST, ALP, γ-GTP) may occur occasionally.
Other Effects: Rarely, dizziness, general fatigue, palpitations, skin rashes, or pruritus may be observed.
6. Drug Interactions
Cardiac Drugs: Concomitant use with β-blockers or antiarrhythmic agents may potentiate cardiac inhibitory effects.
General Precaution: While specific interactions with common gastric medications are limited, caution is advised when combining with other oral therapies.
7. Pharmaceutical Information
Active Ingredient: Troxipide