Ziwei Glutamine Capsules

Brand Name: 自维®(Ziwei®)
Generic Name: Glutamine
Strength: 0.25g per capsule, 40 capsules per box
Manufacturer: Jiangsu Shenhua Pharmaceutical Co., Ltd.
Marketing Authorization Holder: Jiangsu Shenhua Pharmaceutical Co., Ltd.
Approval Date in China: 2001‑03‑26
Registration Number: 国药准字 H20010192
Storage: Store in a sealed, dry place, protected from light.

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1. Indications and Usage
Peptic Ulcers: Indicated for the improvement of symptoms associated with gastric and duodenal ulcers. It aids in the healing process of ulcerative lesions.
2. Dosage and Administration
Standard Dose: The usual dosage for adults is 0.5 g (two capsules) taken orally three times daily.
Administration: It is recommended to take the medication after meals.
Special Populations: For elderly patients, the dose should be reduced appropriately due to decreased physiological function. Safety and efficacy in children have not been fully established.
3. Mechanism of Action
Mucosal Repair: Glutamine plays a significant role in repairing gastrointestinal mucosal damage.
Defense Factor Promotion: It promotes the generation of endogenous defense factors in the normal gastric mucosa.
Ulcer Healing: It stimulates the formation of granulation tissue, which aids in the healing of peptic ulcers.
4. Safety and Warnings
Renal Impairment: Use with caution in patients with renal insufficiency, as the metabolism of amino acids may be impaired.
Pregnancy and Lactation: Use in pregnant or breastfeeding women only if the potential benefit justifies the risk to the fetus or infant.
Allergies: Do not use in patients with known hypersensitivity to glutamine or any ingredients in the capsule.
5. Adverse Reactions and Clinical Research
Common Adverse Reactions: Rare cases of mild gastrointestinal discomfort, such as nausea, constipation, diarrhea, and vomiting.
Other Effects: Some patients may experience facial flushing.
Clinical Findings: Clinical use has demonstrated efficacy in alleviating ulcer-related symptoms and promoting mucosal healing.
6. Drug Interactions
Interaction Status: Specific drug interaction studies have not been conducted, and reliable reference data are currently unavailable.
Precaution: As with many amino acid preparations, caution is advised when combining with other medications, and spacing the administration time is often recommended.
7. Pharmaceutical Information
Active Ingredient: Glutamine (L-2-Aminopentanedioic acid amide).
Strengths: Typically available as 0.25 g capsules.
Appearance: Hard gelatin capsules containing white or off-white granules.
Storage: Store in a light-proof and sealed container, protected from moisture.

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