Xianbixin® is the commercial brand name of Edaravone and Dexborneol Concentrated Solution for Injection. Xianbixin is the Chinese pinyin brand name. It is a compound preparation containing edaravone and dexborneol. Edaravone scavenges free radicals and reduces oxidative stress injury, while dexborneol relieves cerebral edema and improves microcirculation.
Main Indications
Treatment of acute ischemic stroke to improve neurological function deficit.
Clinical Research
Phase 3 clinical trials demonstrated that the combination of edaravone and dexborneol significantly improved neurological impairment in patients with acute ischemic stroke. Compared with edaravone monotherapy, the combined preparation showed better efficacy on functional recovery and reduced cerebral edema.
Common Side Effects
Elevated liver enzymes, rash, nausea;
Other common reactions: injection site reactions, headache. Rare serious adverse events include severe allergic reactions and liver injury.
Approval Status in China
Original drug Xianbixin® (Edaravone and Dexborneol Concentrated Solution for Injection) was officially approved for marketing in China, with the specification of 6 vials per box. It is currently a prescription drug.
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