How much does Giotrif (Afatinib Dimaleate Tablets) Cost& price without insurance in China?
Giotrif® is the commercial brand name of Afatinib Dimaleate Tablets, an orally active irreversible EGFR/HER family tyrosine kinase inhibitor developed by Boehringer Ingelheim. It covalently binds to EGFR, HER2 and HER4 kinase domains to block downstream tumor proliferation signaling pathway.
Main Indications
First-line treatment for locally advanced or metastatic non-small cell lung cancer in adult patients with confirmed activating EGFR gene mutations;
Second-line treatment for squamous cell carcinoma of lung after failure of platinum-based chemotherapy.
Common Side Effects
Common mild adverse reactions: Diarrhea, rash, stomatitis, dry skin and pruritus.
Laboratory abnormalities: Transient elevation of hepatic transaminases.
Severe but manageable risks: Severe intractable diarrhea, interstitial lung disease and severe cutaneous adverse reactions.
Approval Status in China
Giotrif® (Afatinib Dimaleate Tablets, 30mg) was officially approved for marketing in China in 2017. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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