How much does Lonsurf (Trifluridine and Tipiracil Tablets) Cost& price without insurance in China?
Lonsurf® is the commercial brand name of Trifluridine and Tipiracil Tablets, an orally active fixed-combination anticancer agent developed by Japan Taiho Pharmaceutical. Trifluridine inserts into tumor DNA to block cancer cell proliferation, and tipiracil inhibits trifluridine metabolic breakdown to sustain effective drug exposure in vivo.
Main Indications
Treatment of adult patients with RAS wild-type metastatic colorectal cancer previously treated with fluoropyrimidine, oxaliplatin and irinotecan-based chemotherapy, and who have received or cannot tolerate VEGF or EGFR targeted therapies.
Common Side Effects
Common mild adverse reactions: Fatigue, nausea, vomiting, diarrhea and decreased appetite.
Laboratory abnormalities: Neutropenia, anemia and transient liver enzyme elevation.
Severe but manageable risks: Severe bone marrow suppression, severe gastrointestinal adverse events and hypersensitivity reactions.
Approval Status in China
Lonsurf® (Trifluridine and Tipiracil Tablets, 20mg) was officially approved for marketing in China in 2019. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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