How much does Lorbrena (Lorlatinib Tablets) Cost& price without insurance in China?
Lorbrena® is the commercial brand name of Lorlatinib Tablets, an orally active third-generation selective ALK/ROS1 tyrosine kinase inhibitor developed by Pfizer. It potently inhibits mutated ALK kinase to block downstream oncogenic signaling and suppress tumor proliferation, including multiple crizotinib-resistant ALK variants.
Main Indications
Treatment of adult patients with ALK-positive locally advanced or metastatic non-small cell lung cancer who have failed prior ALK inhibitor therapies.
Common Side Effects
Common mild adverse reactions: Hypercholesterolemia, hypertriglyceridemia, edema, peripheral neuropathy and cognitive dysfunction.
Laboratory abnormalities: Elevated blood lipid levels and transient liver enzyme fluctuation.
Severe but manageable risks: Central nervous system adverse reactions, severe hepatic injury and hypersensitivity reactions.
Approval Status in China
Lorbrena® (Lorlatinib Tablets, 100mg) was officially approved for marketing in China in 2022. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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