How much does MaiFantuo (Mavacamten Capsules) Cost& price without insurance in China?
MaiFantuo® is the commercial brand name of Mavacamten, a first-in-class, allosteric and reversible cardiac myosin inhibitor developed by Bristol Myers Squibb. It works by reducing excessive actin-myosin cross-bridge formation, thereby decreasing hypercontractility of the heart muscle and improving left ventricular outflow tract obstruction.
Main Indications
Treatment of adult patients with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM) to improve exercise capacity and symptoms.
Common Side Effects
Common adverse reactions: Dizziness, syncope, decreased left ventricular ejection fraction (LVEF), palpitations, and fatigue.
Severe but manageable risks: Heart failure due to reduced cardiac contractility, which requires close monitoring of LVEF and dose adjustment.
Approval Status in China
MaiFantuo® (Mavacamten Capsules) was officially approved for marketing in China in April 2024, with specifications including 2.5 mg capsules. It is currently a prescription drug and included in China’s Category B medical insurance.
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