How much does Nerlynx (Neratinib Maleate Tablets) Cost& price without insurance in China?
Nerlynx® is the commercial brand name of Neratinib Maleate Tablets, an orally active irreversible pan-HER tyrosine kinase inhibitor developed by Puma Biotechnology. It irreversibly inhibits EGFR, HER2 and HER4 to block downstream oncogenic signaling and restrain tumor cell proliferation.
Main Indications
Extended adjuvant therapy for early-stage HER2-positive breast cancer following completion of trastuzumab-based adjuvant treatment;
Combined with capecitabine for metastatic HER2-positive breast cancer after multiple prior anti-HER2 regimens.
Common Side Effects
Common mild adverse reactions: Diarrhea, nausea, abdominal distension, fatigue and vomiting.
Laboratory abnormalities: Transient elevation of hepatic transaminases.
Severe but manageable risks: Severe refractory diarrhea, severe liver injury and hypersensitivity reactions.
Approval Status in China
Nerlynx® (Neratinib Maleate Tablets, 40mg) was officially approved for marketing in China in 2020. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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