How much does Rujianing (Lerociclib Hydrochloride Tablets) Cost& price without insurance in China?
Rujianing® is the commercial brand name of Lerociclib Hydrochloride Tablets, an orally selective CDK4/6 inhibitor co-developed by G1 Therapeutics and Genor Biopharma. It blocks CDK4/6 kinase activity to arrest tumor cell cycle and suppress proliferation of HR-positive breast cancer cells with continuous daily administration without treatment interruption.
Main Indications
Combined with aromatase inhibitors as first-line therapy for unresectable locally advanced or metastatic HR-positive, HER2-negative adult breast cancer;
Combined with fulvestrant for patients with above breast cancer who have progressed after prior endocrine treatment.
Common Side Effects
Common mild adverse reactions: Neutropenia, fatigue, nausea, anemia and transient hepatic enzyme elevation;
Laboratory abnormalities: Mild thrombocytopenia;
Severe but uncommon risks: Severe myelosuppression, rare interstitial lung injury and hypersensitivity reactions.
Approval Status in China
Rujianing® (Lerociclib Hydrochloride Tablets, 50mg) was officially approved for marketing in China in 2025. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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