How much does Zelboraf (Vemurafenib Tablets) Cost& price without insurance in China?
Zelboraf® is the commercial brand name of Vemurafenib Tablets, an orally active BRAF serine/threonine kinase inhibitor developed by Roche. It selectively inhibits mutant BRAF V600 kinase to block abnormal MAPK signaling pathway and restrain proliferation of BRAF V600-mutated tumor cells.
Main Indications
Monotherapy for unresectable or metastatic malignant melanoma confirmed with BRAF V600 mutation.
Common Side Effects
Common mild adverse reactions: Arthralgia, rash, fatigue, alopecia, nausea and diarrhea.
Laboratory abnormalities: Transient elevation of hepatic transaminases.
Severe but manageable risks: Cutaneous squamous cell carcinoma, severe hypersensitivity and liver function injury.
Approval Status in China
Zelboraf® (Vemurafenib Tablets, 240mg) was officially approved for marketing in China in 2017. It is currently a prescription anti-tumor drug included in China’s Category B medical insurance.
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