Shuqi Troxipide Tablets

1. Indications and Usage
Peptic Ulcer Disease: Treatment of gastric ulcers.
Gastritis: Improvement of gastric mucosal lesions (such as erosion, bleeding, redness, and swelling) associated with acute gastritis and chronic gastritis during acute exacerbation.
2. Dosage and Administration
Adults: Oral administration after meals. The usual dosage is 100 mg three times daily.
Individualization: Dosage may be adjusted according to the patient’s age and symptoms.
3. Mechanism of Action
Mucosal Protection: Troxipide enhances the defense factors of gastric mucosa to promote the repair of ulcerated areas.
Blood Flow: It increases gastric mucosal blood flow and promotes tissue repair. Unlike H2-receptor antagonists, it has no effect on gastric acid secretion.
4. Safety and Warnings
Hypersensitivity: Contraindicated in patients with a known hypersensitivity to troxipide or any components of the formulation.
Special Populations: Use with caution in pregnant women, nursing mothers, the elderly, and children, as safety has not been fully established in these groups.
Hepatic/Renal Dysfunction: Use with caution in patients with hepatic or renal dysfunction.
5. Adverse Reactions and Clinical Research
Gastrointestinal Effects: Occasionally, constipation, abdominal distension, burning sensation in the chest, or nausea may occur.
Hepatic Effects: Elevations in liver function markers (e.g., ALT, AST, ALP, γ-GTP) may occur occasionally.
Other Effects: Rarely, dizziness, general fatigue, palpitations, skin rashes, or pruritus may be observed.
6. Drug Interactions
Cardiac Drugs: Concomitant use with β-blockers or antiarrhythmic agents may potentiate cardiac inhibitory effects.
General Precaution: Caution is advised when combining with other oral medications.
7. Pharmaceutical Information
Active Ingredient: Troxipide.
Chemical Name: (±)3,4,5-Trimethoxy-N-(piperidin-3-yl)benzamide.
Molecular Formula: C15H22N2O4 (Molecular weight: 294.35).
Formulation: Tablets, typically 100 mg per tablet.
Storage: Store in a dry place.