Zhongnan Orazamide Tablets

1. Indications and Usage
Liver Disease Management: Orazamide Tablets are indicated for the adjunctive treatment of acute and chronic hepatitis, fatty liver, and liver cirrhosis.
Symptomatic Relief: Used for alleviating symptoms of alcoholic hepatitis.
2. Dosage and Administration
Standard Dosage: The usual dosage for adults is 0.2 g per dose, taken 3 times daily.
Severity Adjustment: In severe cases, the dose per administration may be increased to 0.6 g – 0.8 g.
Course of Treatment: One course lasts for one month, and usually, 2 to 3 courses are required.
3. Mechanism of Action
Metabolic Regulation: The drug participates in nucleic acid metabolism within the body, correcting abnormalities in protein, fat, and glucose metabolism.
Hepatoprotection: It prevents hepatocyte necrosis and fibrosis, stimulates hepatocyte regeneration, and improves the albumin-to-globulin ratio.
Clinical Benefits: It helps reduce jaundice, improves liver function tests, and can increase urine output and reduce ascites in patients with liver cirrhosis.
4. Safety and Warnings
Contraindications: There are no specific known contraindications; however, the drug should be discontinued if the tablet changes in appearance.
Storage: Keep out of the reach of children.
5. Adverse Reactions and Clinical Research
Common Adverse Reactions: Occasionally, gastrointestinal discomfort and nausea may occur.
6. Drug Interactions
Interaction Data: Specific drug interaction data is not fully established. Concomitant use with other medications may cause interactions; consultation with a physician or pharmacist is advised.
7. Pharmaceutical Information
Active Ingredient: Orazamide (Auramamide Orotate), chemically defined as 4-amino-5-imidazolecarboxamide orotate hydrate.
Strength: Typically available in 0.1 g tablets.
Appearance: Sugar-coated tablets; the core is white or off-white.
Storage: Keep in a light-resistant, tightly closed container, stored in a dry place.