Zongtong Arbidol Hydrochloride Granules

1. Indications and Usage
Upper Respiratory Tract Infection: Treatment of upper respiratory tract infections caused by influenza A and B viruses.
2. Dosage and Administration
Route of Administration: Oral administration ONLY.
Recommended Dosage: Adults: 0.2 g per time, three times daily. The course of treatment is 5 days.
Pediatric Considerations: Clinical data for pediatric use is limited in domestic guidelines.
Critical Administration Instructions:
Renal Impairment: Use with caution in patients with severe renal impairment.
Missed Dose: Take as soon as remembered, but do not double the dose.
3. Mechanism of Action
Viral Fusion Inhibition: It inhibits the fusion of influenza virus lipids with host cell membranes.
Viral Replication Blockade: By preventing virus attachment and entry, it blocks viral replication.
Immunomodulation: It possesses interferon-inducing properties.
4. Safety and Warnings
Sedation: Patients should be advised to avoid operating heavy machinery or driving if dizziness occurs.
Cardiovascular Effects: Heart rate decrease (bradycardia) has been reported. Caution is advised in patients with sinoatrial node lesions or dysfunction.
Hepatic and Renal Impairment: Use with caution in patients with severe liver or kidney dysfunction.
Pregnancy and Lactation: Efficacy and safety during pregnancy and lactation are unclear.
5. Adverse Reactions and Clinical Research
Most Common Adverse Reactions: Nausea, diarrhea, dizziness, and elevated serum transaminases.
Other Adverse Reactions: Laboratory abnormalities may include elevated blood uric acid, lipid metabolism disorders, myalgia, and white blood cell count reduction.
Clinical Research Highlights: Clinical observations have demonstrated significant efficacy in treating acute respiratory viral infections with few adverse events.
6. Drug Interactions
General Interactions: Drug interactions are not yet clear. Please consult a physician or pharmacist if used concurrently with other drugs.
7. Pharmaceutical Information
Chemical Composition: Active Ingredient: Arbidol Hydrochloride.
Appearance: White or off-white granules with a slightly bitter taste.
Packaging: Available in various pack sizes (e.g., 0.1 g/granule).
Storage: Store in a well-closed container, protected from moisture.