How much does Opsumit (Macitentan Tablets) Cost& price without insurance in China?
Opsumit® is the commercial brand name of Macitentan Tablets, an orally active dual endothelin receptor antagonist developed by Actelion. It blocks endothelin receptor subtypes ETₐ and ETᵦ on pulmonary vascular smooth muscle to dilate pulmonary arteries, lower pulmonary vascular resistance and slow progressive pulmonary vascular remodeling.
Main Indications
Long-term treatment of adult pulmonary arterial hypertension (WHO functional class II–III), to reduce the risks of PAH-related disease progression and hospitalizationOPSUMIT®.
Common Side Effects
Common mild adverse reactions: Headache, nasal congestion, anemia, peripheral edema and gastrointestinal upset.
Laboratory abnormalities: Dose-dependent reduction of hemoglobin.
Severe but manageable risks: Severe liver function injury, fetal teratogenicity and severe hypersensitivity reactions.
Approval Status in China
Opsumit® (Macitentan Tablets, 10mg, domestic Chinese brand name: Aopushu) was officially approved for marketing in China in 2017. It is currently a prescription drug included in China’s Category B medical insurance.
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