How much does Welireg (Belzutifan Tablets) Cost& price without insurance in China?

Welireg® is the commercial brand name of Belzutifan Tablets, an orally active hypoxia-inducible factor 2α (HIF-2α) inhibitor developed by MSD. It binds to HIF-2α and inhibits its heterodimerization with HIF-1β, thereby suppressing the transcription of genes involved in angiogenesis, cell proliferation, and tumor growth.

Main Indications
Treatment of adult patients with von Hippel-Lindau (VHL) disease-associated tumors, including renal cell carcinoma (RCC), central nervous system hemangioblastomas, and pancreatic neuroendocrine tumors (pNETs) that require systemic therapy.

Common Side Effects
Common mild adverse reactions: Anemia, fatigue, headache, dizziness, and nausea.
Laboratory abnormalities: Decreased hemoglobin, decreased oxygen saturation, and elevated creatinine.
Severe but uncommon risks: Severe anemia requiring transfusion, hypoxia, and embryo-fetal toxicity.

Approval Status in China
Welireg® (Belzutifan Tablets, 40mg) was officially approved for marketing in China in 2024. It is currently a prescription anti-tumor drug.

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