How much does Trodelvy (Sacituzumab Govitecan for Injection) Cost& price without insurance in China?
Trodelvy® is the international commercial brand name of Sacituzumab Govitecan for Injection, marketed domestically under the Chinese brand name Tuodavi® and developed by Gilead Sciences. It is a Trop-2 targeted antibody-drug conjugate (ADC). The antibody specifically binds to Trop-2 on tumor cells, delivering the conjugated topoisomerase inhibitor SN-38 into tumor cells to induce DNA damage and tumor cell apoptosisTRODELVY®.
Main Indications
Treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer who have received at least two prior systemic therapies, with at least one regimen for metastatic disease.
Treatment of unresectable locally advanced or metastatic HR-positive, HER2-negative breast cancer after failure of endocrine therapy and chemotherapy regimens.
Common Side Effects
Common mild adverse reactions: Neutropenia, diarrhea, fatigue, alopecia, anemia, nausea and vomiting.
Laboratory abnormalities: Decreased neutrophil count, decreased white blood cell count, decreased hemoglobin.
Severe but uncommon risks: Severe neutropenia complicated by infection, severe refractory diarrhea, infusion-related hypersensitivity reactions and severe liver injury.
Approval Status in China
Trodelvy® (domestic brand name Tuodavi®, 180 mg per vial) obtained official marketing approval in China in June 2022. It is a prescription ADC anti-tumor biologic agent.
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