Vigabatrin Powder for Oral Solution is commercially sold under the brand name Weigeding®. It is an irreversible inhibitor of GABA transaminase, which elevates brain GABA levels and exerts anti-seizure effects.
Main Indications
Adjunctive treatment of refractory partial-onset seizures with or without secondary generalization in adult and pediatric patients aged 2 years and older; monotherapy for infantile spasms (West syndrome) in infants aged 1 month and above.
Clinical Research
Global multicenter clinical studies confirmed that vigabatrin can significantly lower seizure frequency among patients with refractory partial epilepsy. For infantile spasms, the medicine shows reliable efficacy in controlling spasms and improving abnormal brain electrical activity, and is recognized as a preferred treatment option in clinical guidelines.
Common Side Effects
Characteristic adverse reaction consists of visual field defects. Other frequent adverse reactions include somnolence, fatigue, dizziness, headache, weight gain, psychiatric symptoms, gastrointestinal discomfort and tremor.
Approval Status in China
Weigeding® (Vigabatrin Powder for Oral Solution) was officially approved for marketing in China in 2024. It is a prescription drug for the treatment of epilepsy.
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