This domestic generic product is marketed under the Chinese brand name Jianketuo®. Tobramycin Inhalation Solution is an inhaled aminoglycoside antibacterial drug. It exerts bactericidal effects by inhibiting bacterial protein synthesis, and high local drug concentration can be achieved in the respiratory tract after atomized inhalation.
Main Indications
For the management of chronic pulmonary infection caused by Pseudomonas aeruginosa in patients with cystic fibrosis.
Clinical Research
Bioequivalence studies confirmed that this domestic generic product has comparable pharmacokinetic characteristics to the original reference product TOBI®. Clinical trials demonstrated that inhaled tobramycin can reduce sputum bacterial load, improve respiratory symptoms and lung function, with controllable local and systemic adverse reactions.
Common Side Effects
Common adverse reactions include cough, bronchospasm, hoarseness, sore throat, tinnitus, hearing loss, and renal function impairment.
Approval Status in China
Jianketuo® (Tobramycin Inhalation Solution) was officially approved for marketing in China in 2022. This domestic generic drug, marketed under brand name Jianketuo® (reference brand name TOBI®). It is a prescription inhaled antibacterial agent.
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