Noxafil® is the commercial brand name of Posaconazole Enteric-coated Tablets, an orally active triazole antifungal developed by MSD. It inhibits fungal lanosterol synthesis by blocking cytochrome P450-dependent 14α-demethylase, resulting in fungal cell membrane damage and bacteriostatic/fungicidal effects. Main IndicationsProphylaxis of…
Florinef® is the commercial brand name of Fludrocortisone Acetate Tablets, an orally active synthetic mineralocorticoid developed by Aspen Pharma. It enhances renal sodium reabsorption and potassium excretion to expand blood volume and regulate electrolyte balance in the body. Main IndicationsReplacement…
Kerendia® is the commercial brand name of Finerenone Tablets, an orally active nonsteroidal mineralocorticoid receptor antagonist developed by Bayer. It selectively blocks mineralocorticoid receptor to reduce renal inflammation and fibrosis, slowing renal function decline. Main IndicationsTreatment of adult patients with…
Opsumit® is the commercial brand name of Macitentan Tablets, an orally active dual endothelin receptor antagonist developed by Actelion. It blocks endothelin receptor subtypes ETₐ and ETᵦ on pulmonary vascular smooth muscle to dilate pulmonary arteries, lower pulmonary vascular resistance…
Adempas® is the commercial brand name of Riociguat Tablets, an orally active soluble guanylate cyclase stimulator developed by Bayer. It stimulates soluble guanylate cyclase to elevate intracellular cGMP concentration, dilate pulmonary vasculature and reduce pulmonary arterial pressure. Main IndicationsTreatment of…
Tracleer® is the commercial brand name of Bosentan Tablets, an orally active dual endothelin receptor antagonist developed by Actelion. It blocks endothelin ETₐ and ETᵦ receptors on pulmonary vascular smooth muscle to relax pulmonary arteries, reduce pulmonary vascular resistance and…
Yuancexin® is the commercial brand name of Recombinant Human Interleukin-2 for Injection, a genetically engineered immunomodulator developed by Beijing Yuance Pharmaceutical Co., Ltd. It activates and proliferates lymphocytes including T cells and NK cells to enhance body anti-tumor immune function.…
Verquvo® is the commercial brand name of Vericiguat Tablets, an orally active soluble guanylate cyclase (sGC) stimulator developed by Bayer. It stimulates soluble guanylate cyclase to increase intracellular cGMP level, dilate blood vessels and reverse adverse cardiac remodeling, thereby alleviating…
Doptelet® is the commercial brand name of Avatrombopag Maleate Tablets, an orally active thrombopoietin receptor agonist developed by Dova Pharmaceuticals. It binds to thrombopoietin receptor on megakaryocytes to stimulate bone marrow megakaryocyte proliferation and differentiation, thereby raising peripheral blood platelet…
Lixiana® is the commercial brand name of Edoxaban Film-coated Tablets, an orally active direct factor Xa inhibitor developed by Daiichi-Sankyo. It selectively blocks coagulation factor Xa to suppress thrombin generation and prevent thrombosis formation. Main IndicationsPrevention of stroke and systemic…