Repatha® is the commercial brand name of Evolocumab Injection, developed by Amgen Manufacturing Limited. It is a fully human monoclonal antibody targeting PCSK9; it blocks the binding between PCSK9 and hepatic LDL receptors to elevate LDL receptor quantity, significantly lowering…
Praluent® is the commercial brand name of Alirocumab Injection, developed by Sanofi. It is a fully human monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9). It blocks the binding of PCSK9 to low-density lipoprotein receptors, increasing hepatic LDL receptor…
Entresto® is the commercial brand name of Sacubitril Valsartan Sodium Tablets, developed by Novartis. It is an oral dual-acting cardiovascular agent combining neprilysin inhibitor and angiotensin II receptor antagonist. It enhances endogenous natriuretic peptide levels while blocking angiotensin receptors, exerting…
EDARBI® is the commercial brand name of Azilsartan Medoxomil Potassium Tablets, developed by Takeda Pharma A It is an oral angiotensin II type 1 receptor antagonist. It selectively blocks angiotensin II receptors on vascular smooth muscle to dilate blood vessels,…
Firazyr® is the commercial brand name of Icatibant Acetate Injection, developed by Takeda. It is a selective bradykinin B2 receptor antagonist. It competitively blocks bradykinin-mediated vasodilation and vascular permeability elevation, rapidly relieving acute edema attacks of hereditary angioedema. Main IndicationsOn-demand…
REBLOZYL® is the commercial brand name of Luspatercept for Injection, developed by Bristol Myers Squibb. It is a first-in-class erythroid maturation agent. It binds to transforming growth factor superfamily ligands to improve late-stage erythroid progenitor cell maturation, reduce ineffective erythropoiesis…
NESP® is the commercial brand name of Darbepoetin Alfa Injection, developed by Kyowa Kirin Co., Ltd. It is a long-acting recombinant human erythropoietin analogue. It binds to erythropoietin receptors on bone marrow erythroid progenitor cells to stimulate red blood cell…
MonoFer® is the commercial brand name of Iron Isomaltoside Injection, developed by Pharmacosmos. It is a stable high-molecular-weight intravenous iron complex. It releases bioavailable ferric iron inside macrophages to replenish systemic iron reserves and stimulate erythropoiesis, enabling single high-dose rapid…
Ferinject® is the commercial brand name of Ferric Carboxymaltose Injection, developed by Vifor (International) Inc. and manufactured by IDT Biologika GmbH. It is a stable intravenous iron preparation with high molecular weight complex structure. It delivers high-dose elemental iron via…
Mulpleta® is the commercial brand name of Lusutrombopag Tablets, developed by Shionogi Inc. It is an oral thrombopoietin receptor agonist. It selectively activates thrombopoietin receptors on bone marrow megakaryocytes to promote megakaryocyte proliferation and maturation, raising peripheral platelet counts and…