Beiwen® is the commercial brand name of Keverprazan Hydrochloride Tablets, a potassium-competitive acid blocker (P-CAB). It reversibly inhibits gastric H⁺/K⁺-ATPase to suppress gastric acid secretion.
Main Indications
Treatment of gastroesophageal reflux disease in adult patients.
Clinical Research
Clinical trials showed that keverprazan achieves rapid and sustained acid suppression after oral administration. It relieves reflux-related symptoms quickly, and demonstrates high healing rates for erosive esophagitis. Compared with proton pump inhibitors, it is less affected by food intake and has a faster onset of action.
Common Side Effects
Systemic reactions: headache, abdominal distension;
Common mild adverse reactions: diarrhea, nausea, flatulence. Rare serious adverse events: hypersensitivity reactions, elevated liver enzymes.
Approval Status in China
Original drug Beiwen® (Keverprazan Hydrochloride Tablets) was officially approved for marketing in China in 2023, with the specification of 10mg. It is currently a prescription gastrointestinal drug.
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