Duozhen® is the commercial brand name of Medium and Long Chain Fat Emulsion, Amino Acids(16) and Glucose(36％) Injection, a ready-to-use triple-chamber parenteral nutrition formulation developed by Kelun Pharmaceutical. It supplies protein, energy and essential fatty acids for patients who cannot receive enteral nutrition.
Main Indications
Parenteral nutrition supply for adult patients who cannot, or are not expected to, receive adequate nutrition via the gastrointestinal tract.
Clinical Research
Multicenter clinical research showed that this triple-chamber bag formulation can effectively maintain patients’ nutritional status, serum albumin and electrolyte levels. It demonstrated non-inferior nutritional efficacy compared with compounded parenteral nutrition mixtures, while lowering compounding-related contamination risk.
Common Side Effects
Hypertriglyceridemia, nausea, vomiting, fever;
Other common reactions: injection site irritation, liver function abnormality. Rare serious adverse events include fat overload syndrome and allergic reactions.
Approval Status in China
Original drug Duozhen® (Medium and Long Chain Fat Emulsion, Amino Acids(16) and Glucose(36％) Injection) was officially approved for marketing in China in April 2022, with the specification of 625ml per bag. It is currently a prescription drug.
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