Latuda® is the commercial brand name of Lurasidone Hydrochloride Tablets, an atypical antipsychotic agent developed by Sunovion Pharmaceuticals. It exerts therapeutic effects through balanced antagonism and partial agonism on multiple central nervous system receptors to improve psychotic symptoms.
Main Indications
Treatment of schizophrenia in adult patients; treatment of depressive episodes associated with bipolar I disorder (bipolar depression) in adult patients.
Clinical Research
Multicenter controlled clinical trials confirmed that lurasidone effectively improves positive and negative symptoms of schizophrenia. For bipolar depression, the drug relieves depressive symptoms without significantly triggering manic conversion, and demonstrates favorable metabolic safety profile compared with many other antipsychotics.
Common Side Effects
Frequently observed adverse reactions include somnolence, akathisia, nausea, parkinsonism and insomnia. It shows low risk of significant weight gain and lipid or glucose metabolism abnormalities.
Approval Status in China
Original drug Latuda® (Lurasidone Hydrochloride Tablets) was officially approved for marketing in China in 2020. It is a prescription antipsychotic medicine.
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