Tecfidera® is the official global commercial brand name developed by Biogen. It is an oral fumarate derivative. It activates the Nrf2 antioxidant signalling pathway, exerts anti‑oxidative and anti‑inflammatory effects, and modulates immune cell function to reduce autoimmune‑mediated central nervous system injury.
Main Indications
Treatment of adult patients with relapsing‑remitting multiple sclerosis (RRMS).
Clinical Research
Global multicenter phase III pivotal trials demonstrated that dimethyl fumarate significantly reduces annual relapse rate, decreases new brain lesion formation and slows disease‑related disability progression in RRMS patients;
Pooled long‑term extension studies confirmed sustained safety and clinical benefits over multi‑year continuous oral administration;
Clinical data including Asian subjects showed consistent efficacy and safety outcomes compared with global study populations.
Common Side Effects
Gastrointestinal adverse reactions: nausea, diarrhoea, abdominal pain, vomiting;
Flushing reactions: facial flushing, skin pruritus and erythema;
Rare but severe risks: progressive multifocal leukoencephalopathy, severe lymphopenia, hepatic injury;
Common mild adverse reactions: headache, fatigue, upper‑respiratory‑tract infection.
Approval Status in China
Original drug Tecfidera® (Dimethyl Fumarate Enteric Capsules) was officially approved for marketing in China in 2021, with the specification of 120 mg. It is currently a prescription drug included in China’s national medical insurance catalogue.
Buy Tecfidera (Dimethyl Fumarate Enteric Capsules) online from China and save up to 80% on costs . no insurance needed . compare prices from a certified HongKong pharmacy .with fast shipping. Contact us now on WhatsApp to get the latest prices.
