Yibitan® is the commercial brand name of Edaravone and Sodium Chloride Injection. Yibitan is the Chinese pinyin brand name. It is a free radical scavenger. By eliminating reactive oxygen species, it suppresses oxidative neuronal damage after cerebral infarction.
Main Indications
Treatment of acute ischemic stroke to improve neurological function deficits.
Clinical Research
Clinical studies showed that edaravone could reduce brain infarct volume and alleviate brain edema after acute cerebral infarction. Early administration within the therapeutic window helps improve patients’ functional outcomes.
Common Side Effects
Elevated transaminases, rash;
Other common reactions: nausea, vomiting. Rare serious adverse events include acute renal injury and severe hypersensitivity.
Approval Status in China
Original drug Yibitan® (Edaravone and Sodium Chloride Injection) was officially approved for marketing in China in 2019, with the specification of 100mL:30mg. It is currently a prescription drug.
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