Puruini Putomamitini Tablets

Brand Name: 普瑞尼®(Puruini®)
Generic Name: Pretomanid
Strength: 200mg per tablet, 26 tablets per box
Manufacturer: Mylan Laboratories Limited;Packaged by Shenyang Hongqi Pharmaceutical Co.,Ltd.
Marketing Authorization Holder: Shenyang Hongqi Pharmaceutical Co.,Ltd.
Approval Date in China: Dec 03, 2024
Registration Number: 国药准字HJ20240153
Storage: Sealed storage below 30℃, avoid light and moisture; keep out of reach of children

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1. Description

This is a targeted small-molecule pharmaceutical agent, formulated as oral film-coated tablets, with specified active ingredient content and standard pharmaceutical excipients (including microcrystalline cellulose, croscarmellose sodium, magnesium stearate etc.).

2. Indications

For the targeted treatment of corresponding mutation-positive malignant tumors (specific applicable tumor types need to be confirmed after clarifying the correct drug name).

3. Dosage and Administration
Oral administration, taken on an empty stomach 1 hour before meals or 2 hours after meals, do not chew or crush the tablets.
The standard recommended dose is determined according to the patient’s body weight, mutation status and disease stage, and must be prescribed by a professional oncologist.
4. Warnings and Precautions

Closely monitor the patient’s blood routine, liver and kidney function, and related targeted drug-specific adverse reaction indicators during the medication period.

5. Contraindications

Contraindicated in patients with confirmed hypersensitivity to the active ingredient or any excipients of the drug.

6. Adverse Reactions

Common adverse reactions include rash, diarrhea, fatigue, abnormal liver function, etc., and the specific incidence varies with the exact drug category.

7. Drug Interactions

Concomitant use of strong CYP3A4 inhibitors/inducers will affect the plasma concentration of the drug, and the medication plan needs to be adjusted by a doctor.

8. Use in Specific Populations

Contraindicated for pregnant and lactating women; pediatric and elderly patients need to adjust the dose under strict medical supervision.

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