How much does SUTENT (Sunitinib Malate Capsules) Cost& price without insurance in China?
SUTENT® is the commercial brand name of Sunitinib Malate Capsules, an orally active, multi-targeted tyrosine kinase inhibitor (TKI) developed by Pfizer. It exerts anti-tumor activity by inhibiting multiple receptor tyrosine kinases, including VEGFR, PDGFR, KIT, FLT3, and RET, thereby suppressing tumor angiogenesis, proliferation, and progression.
Main Indications
Treatment of unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST) after disease progression on or intolerance to imatinib mesylate;
Treatment of advanced renal cell carcinoma (RCC);
Treatment of progressive, well-differentiated pancreatic neuroendocrine tumors (pNET) in patients with unresectable locally advanced or metastatic disease.
Common Side Effects
Common adverse reactions: Fatigue, asthenia, diarrhea, nausea, mucositis/stomatitis, vomiting, dyspepsia, abdominal pain, constipation, hypertension, rash, hand-foot syndrome, and discoloration of skin/hair.
Laboratory abnormalities: Decreased neutrophil count, decreased platelet count, decreased hemoglobin, increased lipase, and increased transaminases.
Severe but manageable risks: Cardiac dysfunction (including left ventricular ejection fraction decline), hemorrhage, hepatotoxicity, thyroid dysfunction, and reversible posterior leukoencephalopathy syndrome (RPLS).
Approval Status in China
SUTENT® (Sunitinib Malate Capsules, 12.5mg) was officially approved for marketing in China in 2007. It is currently a prescription drug included in China’s Category B medical insurance.
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