How much does Anjiayin (Omfiloctocog alfa for Injection) Cost& price without insurance in China?
Anjiayin® is the commercial brand name of Omfiloctocog alfa for Injection, developed by SCT BioPharma. It is a recombinant human coagulation factor VIII produced via gene recombination technology. It supplements deficient endogenous factor VIII in hemophilia A patients, restores normal blood clotting function to control bleeding episodes and prevent hemorrhage during invasive procedures.
Main Indications
On-demand treatment of bleeding episodes in patients with hemophilia A (congenital factor VIII deficiency);
Perioperative hemostatic management for hemophilia A patients receiving surgical interventions;
Long-term regular prophylaxis to reduce recurrent bleeding risk in moderate to severe hemophilia A patients.
Clinical Research
Domestic multicenter clinical trials fully validated its therapeutic value for Chinese hemophilia A patients;
Bleeding control trials confirmed effective cessation of spontaneous and traumatic bleeding after intravenous administration;
Surgical hemostasis observational studies demonstrated stable clotting factor activity support throughout perioperative periods for different types of operations;
Long-term prophylaxis comparative research showed sustained reduction in bleeding frequency and joint damage progression with routine infusion;
Immunogenicity follow-up trials reflected low inhibitor formation incidence with controllable overall adverse reaction spectrum during long-term replacement therapy.
Common Side Effects
Common mild adverse reactions: Injection site erythema, headache, fever, nausea and skin rash;
Laboratory abnormalities: Rare transient mild liver enzyme elevation;
Severe but uncommon risks: Neutralizing factor VIII inhibitor development, severe hypersensitivity and anaphylactic reactions.
Approval Status in China
Anjiayin® (specification 250 IU per vial) obtained marketing approval in China in 2022. It is an injectable prescription orphan drug for hereditary bleeding disorder treatment included in China’s Category B medical insurance catalogue.
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