Asclevir® is the commercial brand name of Ravidasvir Hydrochloride Tablets, a non-structural protein 5A (NS5A) inhibitor for hepatitis C virus. It blocks viral NS5A protein function to disrupt HCV replication and assembly.
Main Indications
In combination with other antiviral agents, for the treatment of chronic hepatitis C virus (HCV) infection in adult patients.
Clinical Research
Clinical trials showed that ravidasvir-based combination therapy achieves high sustained virological response rate at week 12 (SVR12) across multiple HCV genotypes. It demonstrates potent antiviral activity, and maintains efficacy in some patients with baseline resistance-associated substitutions. The treatment course is short with satisfactory tolerability profile.
Common Side Effects
Systemic reactions: headache, fatigue;
Common mild adverse reactions: nausea, insomnia, pruritus. Rare serious adverse events: severe hepatic dysfunction, hypersensitivity reactions.
Approval Status in China
Original drug Asclevir® (Ravidasvir Hydrochloride Tablets) was officially approved for marketing in China in 2022, with the specification of 200mg. It is currently a prescription antiviral drug.
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