Patanol® is the original reference brand name, while the marketed domestic generic product in China has no official English brand name. It is a selective H1 antihistamine agent. It blocks histamine H1 receptors and inhibits release of inflammatory mediators to alleviate allergic symptoms.
Main Indications
For the treatment of allergic rhinitis and chronic spontaneous urticaria in paediatric patients.
Clinical Research
Clinical studies showed that oral olopatadine effectively relieves sneezing, nasal discharge, nasal itching and urticaria wheals. The granule formulation is suitable for young children who cannot swallow tablets. It has low central penetration, so sedative effect is mild at recommended doses.
Common Side Effects
Systemic reactions: somnolence, fatigue;
Common mild adverse reactions: dry mouth, headache, nausea. Rare serious adverse events: hypersensitivity reactions, liver function abnormality.
Approval Status in China
This domestic generic drug was officially approved for marketing in China in 2023, with the specification of 2.5mg per sachet, 12 sachets per box. It is currently a prescription anti-allergy drug.
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