How much does Ruilisheng (Romiplostim N01 for Injection) Cost& price without insurance in China?

Ruilisheng® is the commercial brand name of Romiplostim N01 for Injection, developed by Qilu Pharmaceutical Co., Ltd. It is a thrombopoietin receptor agonist. It selectively binds and activates thrombopoietin receptors on megakaryocytes to stimulate megakaryocyte proliferation and differentiation, elevating peripheral blood platelet counts to reduce bleeding risks.
Main Indications
Second-line treatment of adult patients with immune thrombocytopenia who are insufficiently responsive to corticosteroids, immunoglobulins or splenectomy;
Thrombocytopenia management in patients with chronic liver disease undergoing elective invasive procedures.
Clinical Research
Domestic multicenter registration trials fully validated its platelet-elevating efficacy for Chinese patient populations;
Core efficacy trials confirmed significant sustained platelet count elevation and reduced bleeding event frequency after subcutaneous administration;
Long-term maintenance observational studies demonstrated stable platelet level control with repeated intermittent dosing cycles;
Safety comparative research reflected mild and transient adverse responses during treatment cycles;
Long-term follow-up trials verified low risk of bone marrow reticulin fibrosis and controllable overall safety spectrum for chronic administration.
Common Side Effects
Common mild adverse reactions: Headache, myalgia, arthralgia, fatigue and injection site pain;
Laboratory abnormalities: Rare transient mild bone marrow reticulin deposition;
Severe but uncommon risks: Thromboembolic events, severe hypersensitivity reactions and rebound thrombocytopenia after drug withdrawal.
Approval Status in China
Ruilisheng® (specification 250μg, 1 vial per box) obtained marketing approval in China in 2023. It is an injectable prescription hematological drug included in China’s Category B medical insurance catalogue.
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