How much does TENELIA (Teneligliptin Hydrobromide Tablets) Cost& price without insurance in China?

TENELIA® is the commercial brand name of Teneligliptin Hydrobromide Tablets, developed by Mitsubishi Tanabe Pharma Corporation. It is a long-acting oral DPP-4 inhibitor. It inhibits dipeptidyl peptidase 4 to prolong the activity of endogenous GLP-1 and GIP, regulating blood glucose in a glucose-dependent way without obvious risk of hypoglycemia when used alone.

Main Indications
Improvement of glycemic control in adult patients with type 2 diabetes mellitus, applied as monotherapy or combined with other anti-diabetic agents.

Clinical Research
Global multicenter clinical trials fully verified its therapeutic value. Core glycemic control trials demonstrated its stable and lasting blood glucose lowering effect for long-term management of type 2 diabetes. Comparative tolerability studies showed favorable safety profiles with low incidence of hypoglycemia and weight-neutral characteristics. Long-term follow-up trials confirmed its sustained efficacy and well-controlled adverse event spectrum during prolonged administration.

Common Side Effects
Common mild adverse reactions: Nasopharyngitis, headache, constipation, abdominal distension and skin rash;
Laboratory abnormalities: Rare transient mild elevation of liver enzymes;
Severe but uncommon risks: Severe hypoglycemia (mostly when combined with insulin or sulfonylureas), pancreatitis and hypersensitivity reactions.

Approval Status in China
TENELIA® (domestic brand name Tailian, specification 20mg, 7 tablets per box) obtained official marketing approval in China in 2016. It is an oral prescription anti-diabetic drug included in China’s Category B medical insurance catalogue.

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